Neonatal platelet transfusions: starting again
نویسندگان
چکیده
منابع مشابه
Transfusion Medicine 2 Platelet transfusions
Ever since platelet transfusions were shown to reduce mortality from haemorrhage in patients with acute leukaemia in the 1950s, the use of this therapy has steadily grown to become an essential part of the treatment of cancer, haematological malignancies, marrow failure, and haematopoietic stem cell transplantation. Today, more than 1·5 million platelet products are transfused in the USA each y...
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Platelets represent a crucial part of the normal homeostasis of living organisms by contributing importantly to the maintenance of vascular integrity. Platelets are thus able to respond quickly to a vascular injury, but patients with low circulating platelet levels are at increased risk for bleeding. Such bleeding (minor and serious) can occur either spontaneously or following even minor trauma...
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F OUR YEARS AGO an editorial in Blood identified a number of issues concerning policy decision-making about the clinical use of leukodepleted cellular blood products to prevent HLA-alloimmunization and refractoriness to transfused allogeneic platelets.’ In that editorial, Schiffer concluded that it was premature to recommend platelet leukodepletion for routine use. The issues identified in that...
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Two key questions can be raised about platelet transfusions (PTXs) for neonates (defined for this editorial as preterm infants during the first month following delivery). First, do sound evidence-based guidelines exist to decide when PTX should be given? The short answer is “no”. Second, when a PTX is prescribed, do we know how to select and transfuse the best available platelet product? Fortun...
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ژورنال
عنوان ژورنال: Transfusion Medicine Reviews
سال: 2021
ISSN: 0887-7963
DOI: 10.1016/j.tmrv.2021.06.003